Charlotte, North Carolina (United States of America) - "Headed for Hope 5K". Carolina Neurosurgery & Spine Associates presents the Headed for Hope 5K Run/Walk, making moves for brain tumor research, awareness, and education one step at a time! Will you join us? The race will begin and finish at Carolina Neurosurgery & Spine Associates' Charlotte office on Baldwin Avenue, located in the heart of Midtown. Participants will run along a scenic course through one of the most beautiful neighborhoods of the Queen City. We are delighted to announce our role as hosts for the third annual Headed for Hope 5K, dedicated to raising funds for brain tumor research, awareness, and patient support. Finisher medals, custom race shirt, great awards, food trucks, beer garden, music, and a dance party with Brady the Brain await! www.runsignup.com/Race/NC/Charlotte/HeadedforHope?aflt_token=Nktw0AUB3nF4FPeh7Y7AWqQewFdw9sGt

Parsons, West Virginia (United States of America) - "Blackwater Canyon Half Marathon". The Blackwater Canyon Half Marathon will take place on the Blackwater Canyon railroad grade and Allegheny Highlands Trail running from Thomas, WV to Mill Race Park in Parsons, WV. Please join us for this epic event in support of the Highlands Trail Foundation, a non-profit organization dedicated to trail development in the Potomac Highlands of West Virginia. The Blackwater Canyon Half Marathon is a point-to-point race. The trail is made of pavement, dirt, and crushed stone. The race course will descend about 1400'. The 9:00 am race start is located on the rail trail below First/Front Street in Thomas, WV. The race finish is in Parsons, WV. At 8:00 am, a bus will transport runners from Parsons to the race start in Thomas. Race entry will close at 200 runners! Individual entry fees: before August 13, 2025 - $60; after August 13, 2023 - $75. Awards: custom handmade mugs by MUD Ceramics, Thomas, WV, will be awarded to overall top male and female finisher – Salomon has also donated hydration packs for the overall winners! Top 3 male and female finishers in each age group (0–19, 20–29, 30–39, 40–49, 50–59, 60–69, 70+). Swag: gender-specific shirts, HydraPak speed cup, and locally made finishers woodallions. Please note: we cannot guarantee shirt size after August 13, but will try to have one that works for you. Black-Hel Double: looking for a challenge? In coordination with the West Virginia Mountain Trail Runners' Helvetia 10k Mountain Run, we have the Black-Hel Double! This is a two-part racing event. First complete the Blackwater Canyon Half Marathon on Saturday. Then travel to Helvetia on Sunday and finish the 10k Mountain Run. Finishers of both races receive a special hat with the Black-Hel Double logo. Awards will be given out at the conclusion of the Helvetia 10k Mountain Run. No additional purchase necessary. More information about the Helvetia 10k Mountain Run is available at wvmtr.org/races/helvetia. Race weekend details: packet pickup on Friday evening will take place in Thomas, WV from 5:30–7:00 pm at the rail yard. Race day packet pickup will take place at Mill Race Park in Parsons, WV from 6:45–7:45 am. Shuttle bus leaves Mill Race Park in Parsons for the starting line in Thomas at 8:00 am. Note: please board the bus as soon as you can. The bus ride will take approximately 35–45 minutes. Race start: the race will start at 9:00 am just below Tip Top (on State Hwy 32, Thomas, WV 26292), along the rail yard road. This crushed stone road parallels the North Fork Blackwater River and East Street. Bag drop off: bags and extra layers you need on the bus can be left in the box at the starting line. They will be under the pavilion in the finishers area for you to pick up after the race. Aid stations/restrooms: three aid stations will be provided along the course. Stations will include water, Skratch hydration, and various energy-packed snacks. This will be a cupless race (thank you, HydraPak)! It is suggested that each runner carry the cup provided or water bottle; we won’t have cups at the aid stations. Restrooms are located at the Mill Race Park, Parsons, WV. Portapotties will be provided at the start line. See you there! www.runsignup.com/Race/WV/Parsons/BlackwaterCanyonHalfMarathon?aflt_token=Nktw0AUB3nF4FPeh7Y7AWqQewFdw9sGt

Tigard, Oregon (United States of America) - "KCNA2 Epilepsy Fun Run & Roll". Join us for the 4th annual KCNA2 Epilepsy Fun Run September 14, 2025, as we run, walk, and roll toward our goal to raise $25,000 for research of novel treatments and methods of faster diagnosis to help babies, children, and adults and their families with this rare form of epilepsy live healthier. Gifts from previous years have funded research of KCNA2 Epilepsy leading to earlier diagnosis and putting us on a path toward promising treatments. Even though our understanding is advancing quickly, it is still in early stages and we need your help to develop safe treatments to protect children from the life-threatening effects of KCNA2 Epilepsy. For 2025, we will once again gather in beautiful Tigard, Oregon’s Cook Park to run, walk, or roll and help children and families from all over the United States and the world. The scientists we work with at the University of Toronto and the University of Tübingen, Germany, have found promising compounds to treat KCNA2 made possible by a $25,000 research grant in 2024 fully funded by KCNA2 parents, family members, and friends. Will you help us accelerate advances and treatment options by participating in the 2025 KCNA2 Epilepsy Fun Run, making a gift in honor or support of someone, or by inviting friends and family to support KCNA2 Epilepsy research? Please consider joining us in person in Tigard, OR, host your own event to raise awareness, or make a gift to strengthen support and awareness to help accelerate the pace of research. Event day schedule: 8:15 AM - Packet pick-up and last minute registration; 9:00 AM - 5K and 1 mile run/walks begin; 9:00–10:30 AM - Finish line refreshments, raffle, and gathering; 10:30 AM - Course closes and event ends. Important details: packet pick-up, start, and finish are all located at Shelter 4 of Cook Park, Tigard; all abilities are welcome—run, walk, or roll; the entire course is within Cook Park and all paths are shared with the general public—please be courteous of others and stay to your right; there will not be a bag check so please plan accordingly; free parking is available throughout Cook Park and there are two ADA spots nearby; public restrooms are available near the start/finish; Portland weather can be unpredictable—this event will happen rain or shine; dogs are welcome to join us on the run/walk, but must be on a leash. Registration cost: Early bird (before July 1) - $25 per adult, $15 per child; regular registration (July 1 through August 31) - $30 per adult, $20 per child; late registration (Sept 1–14) - $40 per adult, $25 per child. What's included: bib number, raffle entry, free coffee, and finish line refreshments. T-shirts are available to add to your race packet for an additional fee when you register by August 10. Volunteers needed! If you would like to volunteer for this event, please fill out our form. Virtual option: gather your friends and family and do your Fun Run & Roll wherever you are! Submit your results on RunSignUp or send us a snapshot of your GPS run and we will include them in the final results. Photos are also welcome and encouraged! USA: register by September 1 to receive your packet in the mail before the event date. Registration will be accepted after this date but we cannot guarantee that you will receive your items before the event date. International participants: this option is no longer available. Please consider donating instead of registering. We also encourage you to host your own Fun Run & Roll event in your area! We are happy to support and provide guidance. Host your own event: we encourage those not located near Portland, Oregon to host their own event! It can be as simple as a picnic in the park or as elaborate as you wish. Become a fundraiser on our website, set your donation goal, and get the word out! We can also provide you with a toolkit to give you ideas and help you organize your fundraiser for KCNA2 Epilepsy. We are here to support you along the way. Contact us if you have questions. Learn more: What is KCNA2 Epilepsy? KCNA2-related developmental and epileptic encephalopathy is a neurological disorder caused by a mutation on the KCNA2 potassium channel. The mutation causes the potassium channel to function improperly, resulting in epilepsy and developmental disorders, including autism. There are a variety of complications for each individual, such as intractable seizures, developmental and cognitive delays, and complex medical conditions. Learn more at kcna2epilepsy.org. What is the KCNA2 Epilepsy organization? KCNA2 Epilepsy was founded in 2021 as a 501(c)(3) nonprofit organization with the mission to promote education and awareness so patient-focused research and effective treatments become available. Our vision is to connect families affected by KCNA2 Epilepsy with treatment options and professionals and provide support to improve outcomes. Since our founding less than five years ago, our reach has become global and our reputation as an advocacy and research convener has helped to advance awareness and hope for effective treatments. The KCNA2 Board of Governors is made up of parents and devoted professionals with passion who are dedicated to turning hope for better understanding of potassium channelopathy identification and treatment into real answers. We work with physicians and researchers to deepen understanding and educate parents, other physicians, and researchers. To date, more than 200 families from around the world have benefited from education and new knowledge gained from scientists. Our goal is to raise support to fund research partnerships with leading genetic and epilepsy researchers who will identify effective treatments and early diagnosis of KCNA2 Epilepsy. The need for advocacy, research opportunities, and effective treatment interventions is great, but we hold great hope for new understanding. www.runsignup.com/Race/OR/Tigard/KCNA2AwarenessDay5K?aflt_token=Nktw0AUB3nF4FPeh7Y7AWqQewFdw9sGt

Stillwater, Minnesota (United States of America) - "Log Run Half Marathon". The Log Run Half Marathon, 10 mile, 10K and 5K is a superb, mostly downhill race with a gentle decent ending in downtown Stillwater, Minnesota. It's been known as one of the fastest 10-mile courses around. Participants come back year-after-year for this one and it's easy to see why; it's THE course for personal records. Join us and become its next big fan. www.runstillwater.com/stillwater-log-run

Concord, North Carolina (United States of America) - "Let's Get Moving 5K". Come join us on Saturday, September 20, 2025 at Vietnam Veterans Park in Concord, NC for this great inclusive event for people of all abilities! Let’s get moving for a great event and get all bodies in motion. Proceeds support the work of KennedyStrong Foundation. Event is rain or shine. Choose the 5K, Buddy Run, or Activity Adventure Course! www.runsignup.com/Race/NC/Concord/ALLBODIESINMOTIONEVENT5K1STANNUAL?aflt_token=Nktw0AUB3nF4FPeh7Y7AWqQewFdw9sGt